Two sample MR report
TMEM176A_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | 0.0029799 | 0.1402857 | 0.9836457 |
| Weighted median | 9 | -0.0270448 | 0.0245138 | 0.2699188 |
| Inverse variance weighted | 9 | -0.0421994 | 0.0189682 | 0.0260984 |
| Simple mode | 9 | -0.0142922 | 0.0399381 | 0.7297071 |
| Weighted mode | 9 | -0.0120733 | 0.0391383 | 0.7655985 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.354225 | 7 | 0.8504160 |
| Inverse variance weighted | 3.459875 | 8 | 0.9022814 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0259418 | 0.0798119 | 0.7546518 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002694 | 0 | TRUE | 0.1187561 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
